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Babesiosis: A tick-borne illness on the rise

A red and black adult deer tick climbing a blade of green grass with blurred grass in the background.

You may be familiar with Lyme disease, a bacterial infection from the bite of an infected black-legged tick. While Lyme disease is the most commonly reported tick-borne illness in the United States, another is on the rise: babesiosis. A March 2023 CDC report shows that babesiosis now has a foothold in 10 states in the Northeast and Midwest.

What is babesiosis?

Babesiosis is an illness caused by a parasite (typically Babesia microti) that infects red blood cells. It is spread by infected black-legged ticks (deer ticks). In most cases, the tick must be attached to a person for at least 36 hours to transmit the parasite.

What are the signs and symptoms of babesiosis?

“You may or may not see the tick bite mark on your skin, so your symptoms may be the earliest sign of an infection,” says Dr. Nancy A. Shadick, a rheumatologist and director of the Lyme Disease Prevention Program at Harvard-affiliated Brigham and Women’s Hospital.

Some people with babesiosis experience no symptoms, but the most common symptoms are a combination of

  • severe flulike symptoms such as a high fever (up to 104° F), chills, and sweats, particularly night sweats
  • general discomfort or feeling unwell
  • intense headache
  • muscle and joint pain
  • loss of appetite
  • nausea
  • fatigue.

These symptoms can appear within one to nine weeks, or even several months after a person has been infected.

Less often, babesiosis causes hemolytic anemia. In this form of anemia, red blood cells are destroyed faster than the body can replace them. Signs and symptoms include

  • fatigue
  • dizziness
  • weakness
  • dark urine
  • yellowing skin and whites of the eyes.

Babesiosis can be a severe, life-threatening disease, particularly for adults over age 65 and people with weakened immune systems, such as people without a spleen and those receiving biological therapy or chemotherapy.

Why are cases of babesiosis rising?

Until recently, babesiosis was endemic (consistently present) in seven states: Connecticut, Massachusetts, Minnesota, New Jersey, New York, Rhode Island, and Wisconsin.

However, the CDC report added three more Northeastern states to the list — Maine, New Hampshire, and Vermont — where case rates between 2011 and 2019 matched or even surpassed the other seven states. Vermont cases rose from two to 34, Maine cases from nine to 138, and New Hampshire cases from 13 to 78. The trend is worrisome.

There are several reasons for the rise in babesiosis. “One is warming temperatures driven by climate change, which cause ticks to be more active earlier in the spring and later in the fall,” says Dr. Shadick. Other contributors are an increase in the number of whitetail deer and a rise in housing construction in wooded areas.

How is this tick-borne illness diagnosed and treated?

Babesiosis is diagnosed by a blood test.

It may be treated with specific antibiotics (different than those used for Lyme disease), or with an antibiotic and antimalarial medication. While treatment usually takes seven to 10 days, a longer course may be recommended for people who are immunocompromised.

Can you get Lyme disease and babesiosis?

Yes, though you may also get either one by itself. Some black-legged ticks that carry the Lyme bacterium (Borrelia burgdorferi) also may carry the Babesia parasite, according to Dr. Shadick. “Lyme disease also shares similar symptoms with babesiosis, such as fever, headache, and fatigue,” she says.

How can you prevent tick-borne illnesses?

Tick exposure can occur year-round, but ticks are most active during warmer months. Most cases of babesiosis occur from late spring through early autumn.

Ticks live in grassy, brushy, or wooded areas. Almost any outdoor activity can expose you or your pets to infected ticks, such as camping, walking your dog, and gardening.

To avoid babesiosis and other tick-borne diseases, the CDC offers these tips:

  • Use insect repellents recommended by the Environmental Protection Agency (EPA) containing DEET, picaridin, IR3535, oil of lemon eucalyptus (OLE), para-menthane-diol (PMD), or 2-undecanone. Treat clothing and gear with products containing 0.5% permethrin. Permethrin can treat boots, clothing, and camping gear and remain protective through several washings.
  • Wear light-colored pants and long-sleeved shirts and a hat during outdoor activities.
  • Try to avoid wooded and brushy areas with high grass and leaf litter. Walk in the center of trails.
  • Check clothing, pets, backpacks, and gear for ticks after spending time outdoors.
  • When you come indoors, remove shoes and put clothes in the dryer on high heat for 10 minutes to kill ticks.
  • To remove a tick, use fine-tipped tweezers to grasp the tick as close to the skin’s surface as possible. Pull upward with steady, even pressure. Don’t twist or jerk the tick, as this can cause the mouth-parts to break off and remain in the skin. Clean the bite area with rubbing alcohol or soap and water. Shower within two hours after coming indoors to help remove any unattached ticks. Use the opportunity for a full-body tick check.

For in-depth information about preventing, treating, and living with a tick-borne illness like Lyme disease or babesiosis, see the Lyme Wellness Initiative at Harvard Health Publishing.

About the Author

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Matthew Solan, Executive Editor, Harvard Men's Health Watch

Matthew Solan is the executive editor of Harvard Men’s Health Watch. He previously served as executive editor for UCLA Health’s Healthy Years and as a contributor to Duke Medicine’s Health News and Weill Cornell Medical College’s … See Full Bio View all posts by Matthew Solan

About the Reviewer

photo of Howard E. LeWine, MD

Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing

Howard LeWine, M.D., is a practicing internist at Brigham and Women’s Hospital in Boston, Chief Medical Editor at Harvard Health Publishing, and editor in chief of Harvard Men’s Health Watch. See Full Bio View all posts by Howard E. LeWine, MD

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Dementia: Coping with common, sometimes distressing behaviors

Confused older father with dementia seated on bed, adult son kneeling, holding his hands and talking to himDementia poses many challenges, both for people struggling with it and for those close to them. It can be hard to witness and cope with common behaviors that arise from illnesses like Alzheimer’s disease, vascular dementia, or frontotemporal dementia.

Caring for a person who has dementia may be frustrating, confusing, or upsetting at times. Understanding why certain behaviors occur and learning ways to handle a variety of situations can help smooth the path ahead.

What behaviors are common when a person has dementia?

People with dementia often exhibit a combination of unusual behaviors, such as:

  • Making odd statements or using the wrong words for certain items.
  • Not realizing they need to bathe or forgetting how to maintain good hygiene.
  • Repeating themselves or asking the same question over and over.
  • Misplacing objects or taking others’ belongings.
  • Not recognizing you or remembering who they are.
  • Being convinced that a deceased loved one is still alive.
  • Hoarding objects, such as mail or even garbage.
  • Exhibiting paranoid behavior.
  • Becoming easily confused or agitated.
  • Leaving the house without telling you, and getting lost.

Why do these behaviors occur?

Inside the brain of a loved one with dementia, picture a wildfire shifting course, damaging or destroying brain cells (neurons) and neural networks that regulate our behavior.

What drives this damage depends on the underlying cause, or causes, of dementia. For example, while the exact cause of Alzheimer’s disease is not known, it is strongly linked to proteins that are either gunking up or strangling brain cells. Someone with vascular dementia has experienced periodic insufficient blood flow to certain areas of the brain, causing neurons to die.

“As dementia progresses, the person loses brain cells associated with memory, planning, judgment, and controlling mood. You lose your filters,” says Dr. Stephanie Collier, a psychiatrist at Harvard-affiliated McLean Hospital.

Six strategies for coping with dementia-related behaviors

Dealing with distressing or puzzling dementia-related behavior can require the type of tack you’d take with a youngster. “Due to declines, older adults with dementia can seem like children. But people are generally more patient with children. You should consider using that approach with older adults,” suggests Lydia Cho, a McLean Hospital neuropsychologist.

  • Don’t point out inaccurate or strange statements. “It can make people with dementia feel foolish or belittled. They may not remember details but hold onto those emotions, feel isolated, and withdraw. Instead, put them at ease. Just go with what they’re saying. Keep things light,” Cho says.
  • Don’t try to reason with the person. Dementia has damaged your loved one’s comprehension. Attempting to reason might be frustrating for both of you.
  • Use distraction. This helps when the person makes unreasonable requests or is moderately agitated. “Acknowledge what the person is saying, and change the activity. You could say, ‘I see that you’re upset. Let’s go over here for a minute.’ And then do an activity that engages the senses and relaxes them, such as sitting outside together, listening to music, folding socks, or eating a piece of fruit,” Dr. Collier says.
  • Keep unsafe items out of sight. Put away or lock up belongings the loved one shouldn’t have — especially potentially dangerous items like car keys or cleaning fluids. Consider installing cabinet locks.
  • Supervise hygiene routines. The person with dementia might need a reminder to bathe, or might need to have the day’s clothes laid out on the bed. Or you might need to assist with bathing, shaving, brushing teeth, or dressing.
  • Spend time together. You don’t have to convince your loved one of your identity or engage in fascinating conversation. Just listen to music or do some simple activities together. It will help keep the person from withdrawing further.

Safety is essential when a person has dementia

Sometimes simple strategies aren’t enough when a loved one has dementia.

For example, if the person frequently tries to leave home, you might need to add child-proof covers to doorknobs, install additional door locks or a security system in your home, or get the person a GPS tracker bracelet.

If the person is frequently upset or even violent, you’ll need to call the doctor. It could be that a new medical problem (such as a urinary tract infection) is causing agitation. “If the agitated behavior isn’t due to a new health problem and is predictable and severe, we might prescribe a medication to help regulate mood, such as an antidepressant or an antipsychotic in cases of extreme agitation or hostility,” Dr. Collier says.

As dementia changes, seek the help and support you need

No one expects you to know how to interact with someone who has dementia. There’s a learning curve for all of us, and it continues even after you get a feel for the situation. “The process keeps changing,” Cho says. “What works today may not work next week or the week after that for your loved one. So keep trying different strategies.”

And get support for yourself, such as group therapy for caregivers and their families. You can also find information at the Alzheimer’s Association or Family Caregiver Alliance.

About the Author

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Heidi Godman, Executive Editor, Harvard Health Letter

Heidi Godman is the executive editor of the Harvard Health Letter. Before coming to the Health Letter, she was an award-winning television news anchor and medical reporter for 25 years. Heidi was named a journalism fellow … See Full Bio View all posts by Heidi Godman

About the Reviewer

photo of Howard E. LeWine, MD

Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing

Howard LeWine, M.D., is a practicing internist at Brigham and Women’s Hospital in Boston, Chief Medical Editor at Harvard Health Publishing, and editor in chief of Harvard Men’s Health Watch. See Full Bio View all posts by Howard E. LeWine, MD

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Swimming and skin: What to know if a child has eczema

Three children bobbing in a pool on red, yellow, and green swimming noodles; two are wearing swim googles

Swimming is a great activity for children. It’s good exercise, it’s an important safety skill, and it can be a good way to get outside and get some fresh air and sunshine.

But for children with eczema — also known as atopic dermatitis — swimming can be complicated. Here’s how parents can help.

What is eczema?

Eczema is an allergic condition of the skin. It can be triggered by allergies to things in the environment, like pollen or cats, as well as by allergies to food. It can also be triggered when chemicals or other things irritate the skin, or when the skin loses moisture, or by excessive sweating.

Swimming and sun may be helpful for eczema

Swimming in a chlorinated pool can actually be helpful for eczema. Bleach baths, which are a commonly recommended eczema treatment, essentially make the bathtub like a swimming pool.

It also can be good for eczema to get some sun and be in the water. The trick is to optimize the benefits while preventing the possible problems.

What to do before and after swimming when a child has eczema

Here are some suggestions for parents:

  • If you’ll be outside, make sure you use sunscreen, preferably one with zinc oxide or titanium. Look for formulations for sensitive skin and avoid anything with fragrance. Consider using UV-protectant swimwear or shirts, especially if embarrassment about rashes is a problem.
  • Put on an emollient before swimming, especially in a chlorinated pool. A good grease-up before swimming can protect the skin. Don’t overdo it on the palms or soles; you want your child to be able to hold on to things, and you don’t want them to slip and fall. Talk to your doctor about the best emollient for your child.
  • If you are swimming in a pool for the first time, you might want to try a briefer swim than usual to be sure the chemicals aren’t too irritating. If possible, avoid going in a pool right after chlorine has been added.
  • Plan to change and shower right after swimming, using a mild soap or body wash without fragrance. Dab the skin dry with a clean towel (don’t use the one you used while swimming) and reapply emollient.
  • Look for silicone-lined swim caps and goggles, as they may be less irritating than rubber or other plastics. Be sure to rinse all swim gear after use.
  • If your child’s eczema is very inflamed, or is infected, it might be best to avoid swimming until it is better — or at least to get your doctor’s advice.

What else should you consider?

Be aware that some children and teens with eczema are embarrassed by it and don’t like to wear bathing suits that show a lot of skin. Follow your child’s lead on this.

If your child has frequent flares of eczema, or severe eczema, talk to your doctor about whether using regular topical steroids might help — and whether you should use them before swimming. If you are headed on a vacation where your child will be swimming often, or just headed into a time of year with lots of possible swimming, talk to your doctor about the best strategies to keep your child’s skin healthy.

For more information, visit the websites of the National Eczema Association and the American Academy of Dermatology.

Follow me on Twitter @drClaire

About the Author

photo of Claire McCarthy, MD

Claire McCarthy, MD, Senior Faculty Editor, Harvard Health Publishing

Claire McCarthy, MD, is a primary care pediatrician at Boston Children’s Hospital, and an assistant professor of pediatrics at Harvard Medical School. In addition to being a senior faculty editor for Harvard Health Publishing, Dr. McCarthy … See Full Bio View all posts by Claire McCarthy, MD

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The FDA relaxes restrictions on blood donation

Cartoonish graphic with four pairs of hands holding blood donation bags; tubing marked with blood type leads to red heart in center

While the FDA rules for blood donation were revised twice in the last decade, one group — men who have sex with men (MSM) — continued to be turned away from donating. Now new, evidence-based FDA rules will focus on individual risk rather than groupwide restrictions.

Medical experts consider the new rules safe based on extensive evidence. Let’s review the changes here.

The new blood donation rules: One set of questions

The May 2023 FDA guidelines recommend asking every potential blood donor the same screening questions. These questions ask about behavior that raises risk for HIV, which can be spread through a transfusion.

Blood donation is then allowed, or not, based on personal risk factors for HIV and other blood-borne diseases.

Questions for potential blood donors

Screening questions focus on the risk of recent HIV infection, which is more likely to be missed by routine testing than a longstanding infection.

The screening questions ask everyone — regardless of gender, sex, or sexual orientation — whether in the past three months they have

  • had a new sexual partner and engaged in anal sex
  • had more than one sexual partner and engaged in anal sex
  • taken medicines to prevent HIV infection (such as pre-exposure prophylaxis, or PrEP)
  • exchanged sex for pay or drugs, or used nonprescription injection drugs
  • had sex with someone who has previously tested positive for HIV infection
  • had sex with someone who exchanged sex for pay or drugs
  • had sex with someone who used nonprescription injection drugs.

When is a waiting period recommended before giving blood?

  • Answering no to all of these screening questions suggests a person has a low risk of having a recently acquired HIV infection. No waiting period is necessary.
  • Answering yes to any of these screening questions raises concern that a potential donor might have an HIV infection. A three-month delay before giving blood is advised.

Does a waiting period before giving blood apply in other situations?

Yes:

  • A three-month delay before giving blood is recommended after a blood transfusion; treatment for gonorrhea or syphilis; or after most body piercings or tattoos not done with single-use equipment. These are not new rules.
  • A waiting period before giving blood is recommended for people who take medicines to prevent HIV infection, called PrEP (pre-exposure prophylaxis). PrEP might cause a test for HIV to be negative even if infection is present. The new guidelines recommend delaying blood donation until three months after the last use of PrEP pills, or a two-year delay after a person receives long-acting, injected PrEP.

Who cannot donate blood?

Anyone who has had a confirmed positive test for HIV infection or has taken medicines to treat HIV infection is permanently banned from donating blood. This rule is not new.

Why were previous rules more restrictive?

In 1983, soon after the HIV epidemic began in the US, researchers recognized that blood transfusions could spread the infection from blood donor to recipient. US guidelines banned men who had sex with men from giving blood. A lifetime prohibition was intended to limit the spread of HIV.

At that time, HIV and AIDS were more common in certain groups, not only among MSM, but also among people from Haiti and sub-Saharan Africa, and people with hemophilia. This led to blood donation bans for some of these people, as well.

A lot has changed in the world of HIV in the last several decades, especially the development of highly accurate testing and highly effective prevention and treatment. Still, the rules regarding blood donation were slow to change.

The ban from the 1980s for MSM remained in place until 2015. At that time, rules were changed to allow MSM to donate only if they attested to having had no sex with a man for 12 months. In 2020, the period of sexual abstinence was reduced, this time to three months.

Why are the blood donation guideline changes important?

  • Removing unnecessary restrictions that apply only to certain groups is a step forward in reducing discrimination and stigma for people who wish to donate blood but were turned away in the past.
  • The critical shortage in our blood supply has worsened since the start of the COVID-19 pandemic. These revised rules are expected to significantly boost the number of blood donors.

The bottom line

Science and hard evidence should drive policy regarding blood donation as much as possible. Guidelines should not unnecessarily burden any particular group. These new guidelines represent progress in that regard.

Of course, these changes will be closely monitored to make sure the blood supply remains safe. My guess is that they’ll endure. And it wouldn’t surprise me if there is additional lifting of restrictions in the future.

About the Author

photo of Robert H. Shmerling, MD

Robert H. Shmerling, MD, Senior Faculty Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

Dr. Robert H. Shmerling is the former clinical chief of the division of rheumatology at Beth Israel Deaconess Medical Center (BIDMC), and is a current member of the corresponding faculty in medicine at Harvard Medical School. … See Full Bio View all posts by Robert H. Shmerling, MD